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### Yaoxin Liu Honors Project

**Yaoxin Liu, H'12,**has completed an Honors project titled, "A Mathematical Model: Hepatitis B and Hepatitis D Co-infection." An Honors project is a year-long endeavor culminating in a long Honors thesis and an oral examination by a committee of three examiners. Here is a description of his project: "In this honors project, mathematical models are developed to describe the interaction between human liver cells, hepatitis B virus (HBV) and hepatitis delta virus (HDV). HDV is a dependent virus that can only infect patients who are also HBV-infected, and it causes more severe damage to liver cells than HBV alone. This project is an extension of previous research, which focused on analyzing the impact of immune exhaustion on HBV and HDV infections. Shifting the emphasis to the dynamics of the infections, this honors project will shed light on what causes the severe damage to liver cells. Mathematical models of the system are built from a simpler model of a single infection and used to explore the possible outcomes of HBV and HDV co-infection. Computer simulations are also created to support analytical results. Manipulation the magnitude of different parameters has helped in understanding how different host and viral factors affect the severity of disease." Yaoxin's advisor on this project was Professor Jon Forde.

Posted 13 April 2012

### Marcela Melara Honors Project

**Marcela Melara, WS'12,**has completed an Honors project titled, "ELARA: Environmental Liaison and Automated Recycling Assistant." An Honors project is a year-long endeavor culminating in a long Honors thesis and an oral examination by a committee of three examiners. Here is a description of Marcela's project: "One environmental issue we face today is dealing with the large amounts of landfill garbage. While many efforts are already being made to increase recycling, many people still have trouble identifying and sorting recyclable materials. In order to improve this situation, I designed and built ELARA. This is a new system that facilitates recycling and waste sorting by helping people identify the items which are recyclable and those which are not. The most immediately noticeable aspect of ELARA is a networked kiosk to help users sort their waste correctly. The kiosk is the front end of a larger system of hardware and software." Marcela's advisor for this project was Professor John Vaughn.

Posted 13 April 2012

### Shaun Viguerie Honors Project

**Shaun Viguerie H'12**has completed an Honors project entitled "ISTAT: Online Interface for Hypothesis Testing." An Honors project is a year-long endeavor that culminates with a long Honors thesis and an oral examination by a committee of three examiners. Here is a description of his project: "This honors project involved the creation of an online statistical software application (called ISTAT) for hypothesis testing. The package has a user-friendly interface, and is able to work with data from a variety of different sources. Designed for student use, it supports hypothesis tests commonly covered in introductory statistics courses. The core functionality of the application lies in JavaScript libraries, making it easily extendable. By utilizing many modern web technologies, the project demonstrates the improving capabilities of the web as a platform for complex applications." Shaun's advisor for this project was Professor David Eck.

Posted 13 April 2012

### News from Max Beckett

Posted 22 March 2012

### Movie Night: The Proof

For over 350 years, some of the greatest minds of science struggled to prove what was known as Fermat's Last Theorem -- the idea that a certain simple equation had no solutions. Now hear from the man who spent seven years of his life cracking the problem, read the intriguing story of an 18th century woman mathematician who hid her identity in order to work on Fermat's Last Theorem, and demonstrate that a related equation, the Pythagorean Theorem, is true.

Andrew Wiles devoted much of his career to proving Fermat's Last Theorem, a challenge that perplexed the best minds in mathematics for 300 years. In 1993, he made front-page headlines when he announced a proof of the problem, but this was not the end of the story; an error in his calculation jeopardized his life's work. In this interview, Wiles recounts how he came to terms with the mistake, and eventually went on to achieve his life's ambition.

The department will show the movie on Thursday, December 1st at 7:30pm in Albright Auditorium. Refreshments will be provided. Bring your friends!

Posted 23 November 2011

### If Copernicus and Kepler Had Computers: An Introduction to Model-Building and Computational Science

Posted 11 November 2011

### A Mathematical Model of T Cell Exhaustion Caused by HBV/HDV

Posted 4 November 2011

### Mathematical Models of Bone Biochemistry with Applications to the Treatment of Osteoporosis

On Wednesday, October 26th at 4:30pm in Napier 201 the Department of Mathematics and Computer Science will host Dr. David Ross of Rochester Institute of Technology. Dr. Ross is a SIAM Visiting Lecturer and will be giving a talk entitled: "Mathematical Models of Bone Biochemistry with Applications to the Treatment of Osteoporosis".

In humans and other mammals the skeleton is continuously remodeled, that is, dissolved and rebuilt; human bone has an annual turnover rate of about 10 percent. Understanding the biochemical processes of bone remodeling is important to the development of treatments for the disease osteoporosis, which is characterized by low bone mass, and which puts those who have it at risk of bone fractures. Osteoporosis results from an imbalance in the biochemical remodeling process, when resorption-the chemical breakdown of old bone-outstrips the formation of new bone. The most common cause of osteoporosis is age-related hormone change, the reduction of estrogen in women after menopause, and the reduction of testosterone in older men. Roughly 20 percent of women over the age of 50 have osteoporosis.

In this talk Professor Ross will discuss dynamical system models of bone remodeling that are used to simulate bone remodeling and to study the effects of various treatments for the condition. He will focus on the ways in which the dynamical systems capture the important biochemical features of the remodeling process, and he will discuss modeling methodology and the ways in which models are used. (Refreshments will be served beforehand.)

Posted 20 October 2011

### Two-faced: The Cantor set and notions of size

Posted 23 September 2011

### Departing Faculty

Posted 23 August 2011